Chicken Alfredo Lasagna

Featured in: Weekend Warm-Bake Comforts

This comforting Italian-American classic combines layers of tender chicken breast with velvety Alfredo sauce, fresh spinach, and creamy cheeses between sheets of pasta. Perfect for feeding a crowd, this dish comes together in about 1 hour 25 minutes and serves 8. The creamy ricotta-spinach mixture pairs beautifully with the richness of Alfredo sauce, while mozzarella and Parmesan add depth and a golden finish. Let it rest before slicing for clean, beautiful portions.

Updated on Sun, 18 Jan 2026 10:05:00 GMT
A top-down view of baked Chicken Alfredo Lasagna, showing golden, bubbly mozzarella and Parmesan topping. Pin It
A top-down view of baked Chicken Alfredo Lasagna, showing golden, bubbly mozzarella and Parmesan topping. | hazelflint.com

My sister showed up one Thursday night with a craving she couldnt shake, something creamy and layered but not the same old red sauce lasagna wed grown up with. We stood in my kitchen pulling open cupboards and the fridge, and somehow between her love of Alfredo and my leftover rotisserie chicken, this whole beautiful idea came together. The first pan came out of the oven bubbling at the edges, cheese browning in patches, and we knew wed stumbled onto something wed be making for years. It felt less like following a plan and more like catching lightning in a casserole dish. Now every time I slide that baking dish into the oven, I think of her leaning against my counter, laughing about how we were making it up as we went.

I made this for a potluck once, the kind where everyone brings something and you never know if itll be enough. I watched people go back for seconds, then thirds, scraping the corners of the pan for those crispy cheese bits. One friend asked if Id brought the recipe, and another joked that I wasnt allowed to bring anything else ever again. It became my signature dish without me even trying, the thing people requested for birthdays and quiet Sunday dinners alike. That night I drove home with an empty pan and a group text already asking when Id make it again.

Ingredients

  • Cooked chicken breast: Rotisserie chicken is your best friend here, it saves time and adds a subtle roasted flavor that makes everything taste like you worked harder than you did.
  • Lasagna noodles: Oven ready noodles work in a pinch, but I prefer boiling regular ones al dente so they hold their shape and dont turn mushy under all that sauce.
  • Baby spinach: It wilts down to almost nothing, so dont be shy with the amount, and make sure its chopped roughly so it spreads evenly without clumping.
  • Onion and garlic: Sauteing these first builds a sweet, aromatic base that keeps the Alfredo from feeling too one note or heavy.
  • Alfredo sauce: Homemade is lovely, but a good quality jarred version works beautifully and no one will know the difference once its baked.
  • Ricotta cheese: Whole milk ricotta gives you the creamiest texture, and mixing in an egg helps it set so the layers dont slide apart when you cut into it.
  • Mozzarella and Parmesan: Mozzarella melts into gooey pockets, Parmesan adds sharp, nutty depth, and together they create that golden bubbly top everyone fights over.
  • Italian herbs: A simple blend of dried basil, oregano, and thyme ties everything to its Italian roots without overpowering the creamy sauce.
  • Egg: It binds the ricotta mixture so each slice holds together beautifully on the plate.
  • Fresh parsley: A sprinkle at the end adds a pop of color and a hint of freshness that cuts through all that richness.

Instructions

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Prepare your oven and dish:
Set your oven to 375 degrees and give your baking dish a light coat of butter or oil so nothing sticks. This step feels small but it saves you so much scrubbing later.
Cook the noodles:
If youre using regular lasagna noodles, boil them just until theyre bendable but still have a bit of bite, then lay them flat on a towel so they dont stick together. Oven ready noodles can skip this, but Ill always choose the boiled ones for better texture.
Saute the aromatics:
Warm a little olive oil in a skillet and cook the diced onion until its soft and starting to turn golden, then add the garlic and let it bloom for a minute until your kitchen smells amazing. Dont let the garlic brown or itll turn bitter.
Wilt the spinach:
Toss in the chopped spinach and stir until it collapses into the pan, which happens faster than you think. Let the mixture cool a bit before mixing it into the ricotta so the egg doesnt scramble.
Mix the ricotta filling:
In a bowl, stir together the ricotta, egg, half the Parmesan, the herbs, salt, pepper, and your cooled spinach mixture until its smooth and flecked with green. Taste it and adjust the seasoning, this is your chance to make it perfect.
Start layering:
Spread a thin layer of Alfredo sauce on the bottom of the dish so the noodles dont stick, then lay down your first layer of noodles side by side. Think of it like building a delicious, edible tower.
Build the first layer:
Spread half the ricotta mixture over the noodles, scatter half the chicken on top, drizzle with Alfredo sauce, and sprinkle with mozzarella. Dont worry about perfection, rustic layers taste just as good.
Repeat the second layer:
Add another layer of noodles, the rest of the ricotta mixture, the remaining chicken, more Alfredo, and another handful of mozzarella. Youre halfway there and it already looks incredible.
Finish with the final layer:
Top with your last noodles, pour the remaining Alfredo sauce over everything, and cover it all with the rest of the mozzarella and Parmesan. This top layer will turn golden and bubbly, so be generous.
Bake covered:
Tent the dish with foil and bake for 30 minutes so everything heats through and the flavors meld together. The foil keeps the top from browning too fast.
Bake uncovered:
Remove the foil and bake for another 20 to 25 minutes until the cheese is golden, bubbling, and irresistible. You might hear it sizzling, thats when you know its ready.
Rest before serving:
Let the lasagna sit for 10 to 15 minutes before you cut into it, this lets the layers set so your slices come out clean and beautiful. Garnish with parsley if you want that extra touch of color.
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Layers of tender chicken, spinach, and creamy Alfredo sauce between pasta sheets in Chicken Alfredo Lasagna. Pin It
Layers of tender chicken, spinach, and creamy Alfredo sauce between pasta sheets in Chicken Alfredo Lasagna. | hazelflint.com

There was this one winter evening when the power flickered during a storm and we ate this by candlelight, the kind of unplanned moment that feels more special than any fancy dinner out. My kids were quiet for once, just focused on their plates, and my husband looked up and said it tasted like a hug. I realized then that some recipes dont just fill you up, they anchor you to a moment, a table, a feeling of being exactly where you belong. This lasagna does that every single time.

Make Ahead Magic

You can assemble this entire lasagna up to 24 hours in advance, cover it tightly with plastic wrap and foil, and keep it in the fridge until youre ready to bake. Just add an extra 10 minutes to the covered baking time since its starting cold. I do this all the time when I know Ill have a busy evening, and it feels like a gift to my future self. You can even freeze it unbaked for up to three months, though youll want to thaw it overnight in the fridge before baking. The flavors actually deepen as it sits, so dont be surprised if it tastes even better than you remember.

Swaps and Variations

If you want to stretch this for a crowd or make it a bit lighter, you can swap half the Alfredo sauce for a simple bechamel, which gives you the creaminess without quite as much richness. Kale works beautifully in place of spinach if thats what you have, just make sure to chop it finely and saute it a bit longer. For a gluten free version, use your favorite gluten free lasagna noodles and check that your Alfredo sauce is safe. I once stirred in a handful of sauteed mushrooms with the spinach and it added this earthy depth that made everyone ask what my secret was. You can also use turkey instead of chicken, or even leave the meat out entirely and double the spinach for a vegetarian version that still feels indulgent.

Serving Suggestions

This lasagna is rich and satisfying on its own, but I love pairing it with a crisp green salad dressed in lemon vinaigrette to cut through the creaminess. Garlic bread is always a hit, though honestly you dont need it since the lasagna is already so hearty. A glass of chilled Pinot Grigio or Chardonnay complements the Alfredo beautifully, and if youre serving a crowd, a light sparkling water with lemon feels just as special.

  • Serve it straight from the baking dish for a casual family style meal, or plate individual slices for something a bit more polished.
  • Leftovers reheat perfectly in the microwave or oven, and they make an incredible lunch the next day.
  • If you have any extra Alfredo sauce, warm it up and drizzle it over each slice right before serving for an extra luscious touch.
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A hearty slice of Chicken Alfredo Lasagna on a white plate with fresh parsley garnish and a green salad. Pin It
A hearty slice of Chicken Alfredo Lasagna on a white plate with fresh parsley garnish and a green salad. | hazelflint.com

This Chicken Alfredo Lasagna has become one of those recipes I make without thinking, the kind that feels like muscle memory and comfort all at once. I hope it finds a place at your table, whether thats a quiet Tuesday or a celebration with people you love.

Recipe FAQs

Can I use fresh spinach instead of frozen?

Yes, fresh spinach works wonderfully. Roughly chop about 2 cups of fresh baby spinach and sauté it until wilted before adding to the ricotta mixture. This removes excess moisture and prevents a watery lasagna.

What's the best way to shred chicken for this dish?

Rotisserie chicken is the easiest option and adds excellent flavor. Alternatively, poach or bake chicken breasts and shred them with two forks while still warm. You'll need about 3 cups shredded for this dish.

Can I make this ahead and freeze it?

Absolutely. Assemble the lasagna completely, cover tightly with foil and plastic wrap, then freeze for up to 3 months. Bake from frozen, adding an extra 20-30 minutes to the cooking time and covering with foil initially.

Should I use oven-ready noodles or regular ones?

Either works fine. Oven-ready noodles skip the boiling step and save time. Regular noodles need cooking to al dente first. Both yield equally creamy, delicious results when assembled properly.

How do I prevent the cheese from drying out on top?

Cover the baking dish with foil for the first 30 minutes to trap steam, then remove it to allow the top to brown and bubble. This prevents the cheese from becoming tough while ensuring a golden, bubbly finish.

Can I substitute the ricotta cheese?

Mascarpone or cream cheese can replace ricotta for an even creamier texture. Use the same 2-cup quantity. Cottage cheese is another option, though it may create a slightly different texture.

Chicken Alfredo Lasagna

Rich and creamy lasagna with tender chicken, Alfredo sauce, spinach, and mozzarella between pasta sheets.

Prep Time
30 minutes
Cook Time
55 minutes
Overall Time
85 minutes
Recipe by Vivian Gray


Skill Level Medium

Cuisine Italian-American

Makes 8 Servings

Diet Preferences None specified

Ingredient List

Proteins

01 3 cups cooked chicken breast, shredded or diced

Pasta

01 12 lasagna noodles, regular or oven-ready

Vegetables

01 2 cups fresh baby spinach, roughly chopped
02 1 medium onion, finely diced
03 3 cloves garlic, minced

Sauces & Dairy

01 4 cups Alfredo sauce, store-bought or homemade
02 2 cups whole milk ricotta cheese
03 2 cups shredded mozzarella cheese
04 1 cup grated Parmesan cheese
05 1 large egg

Spices & Seasonings

01 1 teaspoon dried Italian herbs
02 1/2 teaspoon salt
03 1/4 teaspoon black pepper
04 2 tablespoons fresh parsley, chopped

Directions

Step 01

Prepare the baking dish: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish.

Step 02

Cook the pasta: If using regular lasagna noodles, cook according to package instructions until al dente. Drain and set aside.

Step 03

Sauté the aromatics: In a skillet over medium heat, sauté onion in olive oil for 3-4 minutes until softened. Add garlic and cook for 1 minute more.

Step 04

Wilt the spinach: Stir in the chopped spinach and cook until wilted, approximately 2 minutes. Remove from heat and let cool slightly.

Step 05

Prepare the ricotta mixture: In a medium bowl, combine ricotta cheese, egg, half of the Parmesan cheese, Italian herbs, salt, and pepper. Mix in the cooled spinach mixture.

Step 06

Layer the first sauce: Spread 1/2 cup of Alfredo sauce on the bottom of the prepared baking dish.

Step 07

Build the first layer: Layer 4 noodles over the sauce. Spread half of the ricotta-spinach mixture over noodles. Scatter half the chicken on top. Drizzle with 1 cup of Alfredo sauce and sprinkle with 2/3 cup mozzarella.

Step 08

Build the second layer: Repeat with another layer of noodles, remaining ricotta-spinach, remaining chicken, 1 cup Alfredo sauce, and 2/3 cup mozzarella.

Step 09

Top the lasagna: Top with final layer of noodles, remaining Alfredo sauce, remaining mozzarella, and the rest of the Parmesan cheese.

Step 10

Bake covered: Cover with foil and bake for 30 minutes.

Step 11

Finish baking: Remove foil and bake an additional 20-25 minutes until bubbly and golden.

Step 12

Rest and serve: Let stand for 10-15 minutes before slicing. Garnish with fresh parsley if desired.

Necessary Tools

  • 9x13-inch baking dish
  • Large skillet
  • Medium mixing bowl
  • Saucepan
  • Measuring cups and spoons
  • Foil

Allergen Details

Review ingredients for allergens, and always talk to your doctor if you're unsure.
  • Contains wheat from pasta
  • Contains milk
  • Contains eggs
  • May contain tree nuts if using nut-based Alfredo sauce

Nutrition Details (per portion)

Use this nutrition info as a reference only. It‘s not intended as healthcare advice.
  • Calories: 510
  • Fats: 27 g
  • Carbohydrates: 33 g
  • Proteins: 34 g