Spinach & Artichoke Chicken Bake

Featured in: Weekend Warm-Bake Comforts

This spinach and artichoke chicken bake features seasoned chicken breasts topped with a creamy mixture of sautéed spinach, artichoke hearts, Greek yogurt, mozzarella, and Parmesan cheese.

Simply season the chicken, prepare the veggie-cheese topping, spread it over the breasts, and bake at 400°F for 25-30 minutes until golden and bubbly. The result is a tender, flavorful main dish with 48g protein per serving.

Perfect for weeknight dinners, it pairs beautifully with rice, quinoa, or a fresh green salad. Leftovers keep refrigerated for up to three days.

Updated on Tue, 20 Jan 2026 13:48:00 GMT
Golden-brown baked chicken breasts topped with creamy spinach and artichoke mixture, served hot from the oven. Pin It
Golden-brown baked chicken breasts topped with creamy spinach and artichoke mixture, served hot from the oven. | hazelflint.com

The first time I made this spinach and artichoke chicken bake, my husband actually asked if I'd ordered takeout from our favorite Italian restaurant. The smell alone had him wandering into the kitchen, peeking over my shoulder like a curious kid. Something about bubbling cheese and that unmistakable garlic aroma just pulls people to the stove.

Last winter when my sister came over for dinner, she was convinced I'd spent hours at the stove. She kept asking what my secret was, looking for some complicated technique or fancy ingredient. The truth is, the magic happens in the oven while you sip wine and catch up with people you love.

Ingredients

  • 4 boneless, skinless chicken breasts: Look for breasts that are roughly the same thickness so they cook evenly and finish at the same time
  • 1/2 teaspoon kosher salt: This seasons the chicken from within, bringing out its natural sweetness
  • 1/4 teaspoon freshly ground black pepper: Adds a subtle warmth that complements the creamy topping
  • 1 tablespoon olive oil: Creates the perfect base for sautéing the garlic and wilting the spinach
  • 2 cups fresh baby spinach: Baby spinach is tender and cooks down beautifully without any bitter stems
  • 1 (14 oz / 400 g) can artichoke hearts: Canned artichokes work perfectly here, already tender and ready to chop
  • 2 cloves garlic, minced: Fresh garlic is essential for that aromatic depth that permeates the whole dish
  • 1 cup plain Greek yogurt: Whole milk Greek yogurt creates the creamy base while keeping things lighter than cream cheese
  • 1/2 cup shredded mozzarella cheese: Melts into gorgeous, stretchy strands that make the topping irresistible
  • 1/4 cup grated Parmesan cheese: Adds a salty, nutty depth that balances the tangy Greek yogurt
  • 1/4 teaspoon dried oregano: Brings an earthy, herbal note that rounds out the Italian-inspired flavors
  • 1/4 teaspoon crushed red pepper flakes: Just a hint of heat that cuts through the rich, creamy topping

Instructions

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Preheat your oven and prepare the baking dish:
Set your oven to 400°F (200°C) and give a 9x13-inch baking dish a light coating of oil or cooking spray
Season and arrange the chicken:
Sprinkle both sides of each chicken breast with salt and pepper, then place them in a single layer in your prepared dish
Sauté the aromatics:
Warm olive oil in a skillet over medium heat, add garlic for 30 seconds until fragrant, then toss in spinach and cook until just wilted
Make the creamy topping:
In a mixing bowl, combine the wilted spinach, chopped artichokes, Greek yogurt, mozzarella, Parmesan, oregano, and red pepper flakes until everything is well incorporated
Top and bake the chicken:
Spread the spinach and artichoke mixture evenly over each chicken breast, then bake for 25 to 30 minutes until the chicken reaches 165°F (74°C) and the topping is golden and bubbly
Rest before serving:
Let the chicken rest for 5 minutes so the juices redistribute and the topping sets slightly
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Tender chicken breasts smothered in a tangy spinach, artichoke, and Greek yogurt cheese sauce. Pin It
Tender chicken breasts smothered in a tangy spinach, artichoke, and Greek yogurt cheese sauce. | hazelflint.com

This recipe became my go-to for new moms and families needing a comforting meal. Something about warm, bubbly toppings and tender chicken feels like a hug on a plate, the kind of food that says someone cares enough to make you something nourishing.

Making It Your Own

The beauty of this dish lies in its adaptability. I've added sun-dried tomatoes for a sweet, chewy contrast and sautéed mushrooms when I wanted more earthiness. Once I even threw in some chopped roasted red peppers because that's what was lurking in the fridge, and it turned out fantastic.

Perfect Pairings

A crisp green salad with a bright vinaigrette cuts through the richness perfectly. I've also served it over fluffy quinoa for extra protein and alongside roasted broccoli for a complete meal that still feels light despite the cheesy topping.

Make-Ahead Magic

You can assemble everything up to a day in advance and store it covered in the refrigerator. The topping actually benefits from sitting, as the flavors meld together beautifully.

  • Let the dish sit at room temperature for 20 minutes before baking if it has been refrigerated
  • Add 5 to 10 minutes to the baking time if the chicken is cold from the refrigerator
  • The topping can be made up to 3 days ahead and stored separately if you prefer
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Easy weeknight dinner: baked chicken with bubbly, golden spinach and artichoke topping. Pin It
Easy weeknight dinner: baked chicken with bubbly, golden spinach and artichoke topping. | hazelflint.com

There's something deeply satisfying about a recipe that feels indulgent but still keeps things balanced and wholesome. This dish has become one of those meals I return to again and again, always greeted with the same happy anticipation around the table.

Recipe FAQs

Can I prepare this dish ahead of time?

Yes, you can assemble the bake up to 24 hours in advance. Prepare the chicken and topping, cover with plastic wrap, and refrigerate. Bake directly from the fridge, adding 5-10 minutes to the cooking time.

What's the best way to check if the chicken is fully cooked?

Use a meat thermometer inserted into the thickest part of the chicken breast. It should read 165°F (74°C). Alternatively, cut into the thickest piece—the juices should run clear with no pink.

Can I substitute Greek yogurt with regular yogurt?

Greek yogurt works best due to its thickness and tanginess, but you can use regular yogurt. Since it's thinner, drain it well first or use less to prevent a watery topping. Alternatively, mix half Greek yogurt with half cream cheese for richness.

How should I store and reheat leftovers?

Store covered in an airtight container in the refrigerator for up to 3 days. Reheat gently in a 350°F oven for 10-15 minutes until warmed through. You can also reheat individual portions in the microwave for 1-2 minutes.

What vegetables work well as additions to this dish?

Sautéed mushrooms, sun-dried tomatoes, roasted red peppers, or caramelized onions complement the spinach and artichoke beautifully. Add them to the yogurt mixture before spreading over the chicken for extra flavor and texture.

Is this naturally gluten-free?

Yes, all ingredients listed are naturally gluten-free. However, always check individual product labels for cross-contamination warnings if you have a severe gluten sensitivity or celiac disease.

Spinach & Artichoke Chicken Bake

Tender chicken breasts baked under creamy spinach and artichoke topping with Greek yogurt and cheese.

Prep Time
15 minutes
Cook Time
30 minutes
Overall Time
45 minutes
Recipe by Vivian Gray


Skill Level Easy

Cuisine American

Makes 4 Servings

Diet Preferences No Gluten

Ingredient List

Chicken

01 4 boneless, skinless chicken breasts (about 1.5 lbs)
02 1/2 teaspoon kosher salt
03 1/4 teaspoon freshly ground black pepper

Spinach & Artichoke Topping

01 1 tablespoon olive oil
02 2 cups fresh baby spinach, roughly chopped
03 1 (14 oz) can artichoke hearts, drained and coarsely chopped
04 2 cloves garlic, minced
05 1 cup plain Greek yogurt
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1/4 teaspoon dried oregano
09 1/4 teaspoon crushed red pepper flakes

Directions

Step 01

Prepare the Baking Dish and Chicken: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish. Season chicken breasts with salt and pepper, then arrange in a single layer in the prepared dish.

Step 02

Sauté the Aromatics and Spinach: Heat olive oil in a skillet over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Add chopped spinach and cook until just wilted, approximately 2 minutes.

Step 03

Combine the Topping Mixture: In a mixing bowl, combine the sautéed spinach, chopped artichoke hearts, Greek yogurt, mozzarella, Parmesan, oregano, and crushed red pepper flakes. Mix until well combined.

Step 04

Assemble and Bake: Spread the spinach and artichoke mixture evenly over the chicken breasts. Bake for 25 to 30 minutes until the chicken reaches an internal temperature of 165°F and the topping is golden and bubbly.

Step 05

Rest and Serve: Remove from oven and let rest for 5 minutes before serving.

Necessary Tools

  • 9x13-inch baking dish
  • Skillet
  • Mixing bowl
  • Knife and chopping board
  • Measuring cups and spoons

Allergen Details

Review ingredients for allergens, and always talk to your doctor if you're unsure.
  • Contains dairy (Greek yogurt, mozzarella, Parmesan)
  • May contain eggs if using egg-enriched cheese
  • Gluten-free as written; verify labels for potential cross-contamination

Nutrition Details (per portion)

Use this nutrition info as a reference only. It‘s not intended as healthcare advice.
  • Calories: 325
  • Fats: 11 g
  • Carbohydrates: 7 g
  • Proteins: 48 g